Thanks to the ANN for finding this amusing gem.
The protest is by Palestinians against the violent killing of children in the occupied territories. Which I have to admit is a dark and serious subject.
But then the picture they chose to depict children is Suzumiya Harumi from the light novel/manga/anime series “The melancholy of Suzumiya Haruhi”.
As someone who has watched and enjoyed the series I can tell you a little bit of the plot without spoiling it too much for you.
Haruhi is God. [Although she is unaware of that.]
Or at least that is one of the theories as to why varies people and organizations, from aliens to time travellers, are interested in a seemingly ordinary high-school girl.
Since the anime aired any reference to God, or religion in general, on the many anime/manga image boards, tends to be associated with an image of Haruhi. [Amusingly I also have Haruhi as my desktop image at the moment.]
So the idea of a Moslem using the image of Haruhi in a protest, especially after the furore earlier this year about the danish cartoons of Mohamed, is mildly amusing. [It is also reminiscent of the “evil Bert” next to Osama picture.]